Sjögren’s Syndrome

Conveniently located to serve Denver Metro, Fort Collins, and Colorado Springs.

Functional Medicine’s Approach to Sjögren’s Syndrome


Welcome to Spire Health Pathways, where our functional medicine practice is devoted to empowering individuals living with Sjögren’s Syndrome through comprehensive knowledge and personalized care. This webpage offers an extensive and detailed look at Sjögren’s Syndrome, its signs and symptoms, the impact on people’s lives, and what to expect from our practice when seeking care. Our aim is to help you make well-informed decisions about your health and the management of this condition.

Understanding Sjögren’s Syndrome

What is Sjögren’s Syndrome?

Sjögren’s Syndrome is a chronic autoimmune disorder where the body’s immune system mistakenly attacks its own moisture-producing glands, primarily the salivary and tear glands. This results in dryness of the mouth, eyes, and other areas of the body. Sjögren’s Syndrome can occur as primary (not associated with another autoimmune disease) or secondary (when it occurs alongside another autoimmune disease, such as rheumatoid arthritis or lupus).

Causes and Risk Factors

The exact cause of Sjögren’s Syndrome is unknown, but it is believed to involve a combination of genetic, environmental, and hormonal factors. Some individuals may have a genetic predisposition to the disease, making them more susceptible to developing it. Environmental factors, such as viral or bacterial infections, may trigger the immune system’s abnormal response. Hormonal factors, particularly estrogen, may also play a role in the development of Sjögren’s Syndrome. The condition is more common in women and typically presents between the ages of 40 and 60.

Signs and Symptoms of Sjögren’s Syndrome

Primary Symptoms

The hallmark symptoms of Sjögren’s Syndrome are dry eyes and dry mouth. Dry eyes, or keratoconjunctivitis sicca, occur when the tear glands do not produce enough tears or when the tears evaporate too quickly. This can cause a gritty, burning sensation in the eyes, sensitivity to light, and vision problems. Dry mouth, or xerostomia, occurs when the salivary glands do not produce enough saliva. This can lead to difficulties speaking, chewing, and swallowing, as well as an increased risk of dental issues, such as cavities and gum disease.

Additional Symptoms

Sjögren’s Syndrome can also cause a range of other symptoms, which may vary greatly among individuals. These can include:

  • Fatigue
  • Joint pain and stiffness
  • Dry skin
  • Vaginal dryness
  • Persistent dry cough
  • Swollen salivary glands
  • Raynaud’s phenomenon (a condition that affects blood flow to the fingers and toes)
  • Gastrointestinal issues, such as acid reflux and difficulty swallowing
  • Neurological symptoms, including numbness, tingling, and weakness

Diagnosing Sjögren’s Syndrome

Diagnosing Sjögren’s Syndrome can be challenging, as its symptoms are often similar to those of other conditions. A comprehensive evaluation, including a detailed medical history, physical examination, and various tests, is necessary to confirm the diagnosis. Some of the tests that may be used in the diagnostic process include:

Blood Tests

Blood tests may be used to identify specific autoantibodies (proteins produced by the immune system that mistakenly target healthy tissue) and other markers associated with Sjögren’s Syndrome. These may include:

  • Anti-SSA/Ro and anti-SSB/La antibodies
  • Erythrocyte sedimentation rate (ESR)
  • C-reactive protein (CRP)
  • Complete blood count (CBC)
  • Antinuclear antibodies (ANA)

Ocular Tests

Tests to evaluate eye dryness and function may be performed. These can include:

  • Schirmer’s test: This measures the production of tears by placing small strips of paper under the lower eyelids.
  • Slit-lamp examination: A specialized microscope is used to examine the surface of the eye for signs of dryness and inflammation.
  • Tear film break-up time: This test measures the time it takes for tears to evaporate from the surface of the eye.

Oral Tests

  • Tests to assess salivary gland function and the presence of inflammation may be conducted. These can include:
  • Sialometry: This measures saliva production by collecting saliva in a small tube for a specific period of time.
  • Salivary gland biopsy: A small tissue sample is taken from a salivary gland, usually in the lip, and examined for signs of inflammation and damage.

Traditional Medicine Treatment Options

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Symptomatic Management

The primary goal of traditional treatment for Sjögren’s Syndrome is to manage symptoms and improve quality of life. This can include:

  • – Artificial tears and eye ointments for dry eyes
  • – Saliva substitutes and oral lubricants for dry mouth
  • – Nonsteroidal anti-inflammatory drugs (NSAIDs) for joint pain and inflammation
  • – Immunosuppressive medications, such as corticosteroids or disease-modifying antirheumatic drugs (DMARDs), for severe cases
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Preventive Care

Preventive care is essential to minimize the risk of complications associated with Sjögren’s Syndrome. This can involve:

  • – Regular dental checkups and cleanings
  • – Fluoride treatments to protect teeth
  • – Protective eyewear to reduce eye irritation
  • – Maintaining good hygiene and skincare practices

Functional Medicine Approach at Spire Health Pathways

At Spire Health Pathways, our functional medicine approach to Sjögren’s Syndrome seeks to address the underlying causes and triggers of the condition, rather than solely focusing on symptom management. Our personalized treatment plans are designed to promote overall health and well-being by addressing each individual’s unique needs and circumstances.

Comprehensive Assessment

We begin with a thorough evaluation of your medical history, lifestyle factors, and environmental influences. This allows us to identify potential triggers and imbalances that may be contributing to the development or exacerbation of Sjögren’s Syndrome.

Personalized Treatment Plans

Based on our comprehensive assessment, we develop a personalized treatment plan that addresses the root causes of your symptoms and supports your overall health. This can include:

  • Nutritional counseling and personalized meal planning
  • Targeted supplementation to address nutritional deficiencies and support immune system regulation
  • Lifestyle modification recommendations, such as stress reduction techniques, sleep optimization, and personalized exercise plans
  • Integrative therapies, such as acupuncture, massage therapy, or hydrotherapy, to support overall health and well-being


At Spire Health Pathways, our goal is to provide comprehensive, personalized, and integrative care for individuals living with Sjögren’s Syndrome. We believe that by addressing the root causes of the condition and supporting overall health and well-being, we can help you achieve optimal health and improve your quality of life. If you or a loved one is living with Sjögren’s Syndrome and would like to explore our functional medicine approach, we invite you to contact us and schedule a consultation. Let us partner with you on your journey to better health and wellness.

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Unexplained Symptoms

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Lifestyle & Environmental

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Autoimmune & Allergic

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Neurologic & Mental Health

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Spire Health Pathways

“The doctor of the future will give no medicine, but will instruct his patients in care of the human frame, in diet, and in the cause and prevention of disease.” – Thomas Edison